Cognitive rehabilitation of mildly impaired Alzheimer disease patients on cholinesterase inhibitors. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: The authors evaluated the efficacy of a new cognitive rehabilitation program on memory and functional performance of mildly impaired Alzheimer disease (AD) patients receiving a cholinesterase inhibitor. METHODS: Twenty-five participants in the Cognitive Rehabilitation (CR) condition participated in two 45-minute sessions twice per week for 24 total sessions. CR training included face-name association tasks, object recall training, functional tasks (e.g., making change, paying bills), orientation to time and place, visuo-motor speed of processing, and the use of a memory notebook. Nineteen participants in the Mental Stimulation (MS) condition had equivalent therapist contact and number of sessions, which consisted of interactive computer games involving memory, concentration, and problem-solving skills. RESULTS: Compared with the MS condition, participants in CR demonstrated improved performance on tasks that were similar to those used in training. Gains in recall of face-name associations, orientation, cognitive processing speed, and specific functional tasks were present post-intervention and at a 3-month follow-up. CONCLUSION: A systematic program of cognitive rehabilitation can result in maintained improvement in performance on specific cognitive and functional tasks in mildly impaired AD patients.

publication date

  • January 1, 2004

Research

keywords

  • Alzheimer Disease
  • Cognition Disorders
  • Cognitive Behavioral Therapy

Identity

Digital Object Identifier (DOI)

  • 10.1176/appi.ajgp.12.4.395

PubMed ID

  • 15249277

Additional Document Info

volume

  • 12

issue

  • 4