Thiourea inhibitors of herpesviruses. Part 3: Inhibitors of varicella zoster virus. Academic Article uri icon

Overview

abstract

  • The preparation of alpha-methylbenzyl thioureas and their biological activity against varicella zoster virus is described. Several analogs demonstrated IC50s<0.1 microM and their SAR are discussed. These compounds represent a novel class of potent and selective nonnucleoside inhibitors of varicella zoster virus.

publication date

  • August 16, 2004

Research

keywords

  • Antiviral Agents
  • Herpesvirus 3, Human
  • Thiourea

Identity

Scopus Document Identifier

  • 3142737987

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2004.06.025

PubMed ID

  • 15261261

Additional Document Info

volume

  • 14

issue

  • 16