Prolonged survival following salvage surgery for chemorefractory ovarian immature teratoma: a case report and review of the literature. Review uri icon

Overview

abstract

  • BACKGROUND: Data regarding salvage surgery for ovarian immature teratoma (IT) are lacking despite its established role in the management of chemorefractory testicular germ cell tumors. In this report, a case of advanced IT that was salvaged by secondary cytoreduction following failure of both primary therapy and salvage chemotherapy is described, and the available literature is reviewed. CASE: A 28-year-old patient underwent primary cytoreductive surgery followed by platinum-based chemotherapy for stage IIIC, grade 3, ovarian IT. Second-line chemotherapy was administered after residual disease was identified at second-look surgery. Following failure of salvage chemotherapy, aggressive secondary debulking resulted in long-term disease-free survival of over 48 months. CONCLUSION: There appears to be a distinct role for salvage surgery in selected cases of chemorefractory IT. More studies are needed to further define the subset of patients who benefit most from this management approach.

publication date

  • March 1, 2005

Research

keywords

  • Ovarian Neoplasms
  • Teratoma

Identity

Scopus Document Identifier

  • 13844256723

Digital Object Identifier (DOI)

  • 10.1016/j.ygyno.2004.11.035

PubMed ID

  • 15721445

Additional Document Info

volume

  • 96

issue

  • 3