HER2 codon 655 polymorphism and breast cancer: results from kin-cohort and case-control analyses. Review uri icon

Overview

abstract

  • Several published epidemiologic studies show increased breast cancer risk for carriers of the Val-allele at codon 655 of the HER2 gene. We conducted additional analyses using data from three studies, including case-control analyses stratified on age and kin-cohort analyses using relatives of cases and controls. The results provide additional evidence that HER2 codon 655 genotype may predispose to early-onset breast cancer.

publication date

  • February 1, 2005

Research

keywords

  • Breast Neoplasms
  • Codon
  • Genes, erbB-2
  • Polymorphism, Genetic

Identity

Scopus Document Identifier

  • 18444372055

Digital Object Identifier (DOI)

  • 10.1007/s10549-004-2171-5

PubMed ID

  • 15754131

Additional Document Info

volume

  • 89

issue

  • 3