Leptomeningeal metastases from leukemias and lymphomas. Review uri icon

Overview

abstract

  • Leptomeningeal dissemination of lymphoma and leukemia differs from that of solid tumors in a number of clinically important aspects. Specific histologic variants of lymphoma and leukemia have such a high incidence of cerebrospinal fluid (CSF) dissemination that assessing CSF cytology at diagnosis is crucial and prophylactic therapy of the CSF compartment is required. Furthermore, while the overall prognosis for patients with leptomeningeal metastases from leukemia and lymphoma is similar to solid tumors, selected patients have excellent response to therapy and attain durable remission. Therefore, aggressive treatment is warranted.

publication date

  • January 1, 2005

Research

keywords

  • Leukemia
  • Lymphoma
  • Meningeal Neoplasms

Identity

Scopus Document Identifier

  • 27744546809

Digital Object Identifier (DOI)

  • 10.1007/0-387-24199-x_4

PubMed ID

  • 16211883

Additional Document Info

volume

  • 125