A case of monophasic synovial sarcoma presenting as a vulvar mass. uri icon

Overview

abstract

  • BACKGROUND: Synovial sarcoma is the fourth most commonly occurring sarcoma, accounting for 8-10% of all sarcomas. They arise from unknown pleuripotent stem cells that are capable of differentiating into mesenchymal and/or epithelial structures. Synovial sarcoma is characterized by specific chromosomal translocation t (X; 18)(p11, q11). CASE: We report the first case of monophasic synovial sarcoma arising in soft tissues of the vulva in a 33-year-old female. Complete excision of the mass was possible with tumor-free margins. CONCLUSION: Only four previous cases of biphasic synovial sarcoma arising in the vulva have been reported. The finding of the SYT-SSX2 translocation is generally associated with a better prognosis, besides tumor negative margins after excision offer the possibility of a better outlook for this patient.

publication date

  • October 14, 2005

Research

keywords

  • Sarcoma, Synovial
  • Vulvar Neoplasms

Identity

Scopus Document Identifier

  • 30444441054

Digital Object Identifier (DOI)

  • 10.1016/j.ygyno.2005.09.013

PubMed ID

  • 16226798

Additional Document Info

volume

  • 100

issue

  • 2