BACKGROUND: An 81-year-old man presented with a history of right nephrectomy for renal cell carcinoma, chronic renal insufficiency and implanted defibrillator. He was asymptomatic. Contrast-enhanced CT and MRI were contraindicated. INVESTIGATIONS: Non-contrast CT, positron emission tomography (PET), fused PET-CT and Doppler ultrasound. DIAGNOSIS: Small exophytic left midpole renal tumor, 3.7 cm in size. MANAGEMENT: Percutaneous CT-guided renal cryoablation, followed up with PET-CT imaging.