Modest hypothermia as a neuroprotective strategy in high-risk term infants. Review uri icon

Overview

abstract

  • This article briefly reviews the pathogenesis of hypoxic-ischemic cerebral injury, the experimental data, and clinical studies that have evaluated the potential therapeutic benefit of modest selective or whole body hypothermia in reducing the subsequent development of irreversible brain injury without untoward side effects. Data are insufficient to recommend routine use of either modest selective or whole body hypothermia after resuscitation of infants with suspected asphyxia. Further clinical trials are needed to determine which infants would benefit most and which method of cooling would be most effective.

publication date

  • March 1, 2006

Research

keywords

  • Hypothermia, Induced
  • Hypoxia-Ischemia, Brain

Identity

Scopus Document Identifier

  • 33644926379

Digital Object Identifier (DOI)

  • 10.1016/j.clp.2005.11.012

PubMed ID

  • 16533643

Additional Document Info

volume

  • 33

issue

  • 1