Endoscopic treatment for atypical manifestations of gastroesophageal reflux disease. Academic Article uri icon

Overview

abstract

  • OBJECTIVES: Atypical manifestations are common in patients with gastroesophageal reflux disease (GERD). The aim of this study was to evaluate the response of atypical manifestations of GERD to endoscopic antireflux treatment. METHODS: Patients with atypical manifestations of GERD including hoarseness, cough, wheezing, and non-cardiac chest pain were studied. Endoscopic antireflux treatment consisted of placement of sutures below the squamo-columnar junction. Clinical response was defined as complete resolution of the atypical symptom. Patients were followed clinically for up to 3 yr after the procedure. Short-term response was evaluated within 6 months of the procedure, and long-term follow-up was determined 1-3 yr after the procedure. RESULTS: Forty-three patients met the inclusion criteria; four patients underwent repeat procedures during the study period and were excluded from the analysis. Long-term follow-up was available in all 39 patients. Short-term response counts were: hoarseness, 12 of 19 patients, cough, 17 of 19; wheezing, 8 of 9; and chest pain, 13 of 18. Long-term follow-up of patients (mean of 18 months) for these symptoms was not significantly different compared to short-term response. CONCLUSIONS: Endoscopic suturing of the gastroesophageal junction appears to be a possible treatment option for atypical manifestations of GERD and future studies are needed to determine its role in management.

publication date

  • March 1, 2006

Research

keywords

  • Chest Pain
  • Cough
  • Esophagogastric Junction
  • Esophagoscopy
  • Fundoplication
  • Gastroesophageal Reflux
  • Hoarseness
  • Suture Techniques

Identity

Scopus Document Identifier

  • 33644769547

Digital Object Identifier (DOI)

  • 10.1111/j.1572-0241.2006.00496.x

PubMed ID

  • 16542278

Additional Document Info

volume

  • 101

issue

  • 3