Ontogeny of ingestive behavior. Review uri icon

Overview

abstract

  • Review of the ontogeny of the controls of independent ingestion reveals that some of the direct and indirect controls of meal size identified in adult rats function in the first three postnatal weeks. The controls appear sequentially and some of them change their potency after they emerge. Indirect controls exerted by metabolism and adiposity do not emerge until the fourth postnatal week or later in the postweaning period. Recent experiments in rats with monogenic obesities involving the leptin and cholecystokinin receptors have demonstrated the usefulness of independent ingestion in the detection of the earliest expression of hyperphagia. Although much remains to be learned about the normal controls of independent ingestion, it is clear that it provides relevant information about the development of normal and abnormal controls of meal size in rodents that is useful for translational research into the controls of meal size in normal and obese children.

publication date

  • July 1, 2006

Research

keywords

  • Feeding Behavior

Identity

Scopus Document Identifier

  • 33746267306

Digital Object Identifier (DOI)

  • 10.1002/dev.20145

PubMed ID

  • 16770762

Additional Document Info

volume

  • 48

issue

  • 5