Percutaneous computerized tomography guided cryoablation for localized renal cell carcinoma: factors influencing success. Academic Article uri icon

Overview

abstract

  • PURPOSE: We evaluated the factors that influenced the initial success rate and complication rate of percutaneous computerized tomography guided cryoablation of localized renal cell carcinoma of clinical stage T1N0M0. MATERIALS AND METHODS: A total of 21 patients with a mean age of 71.5 years and a pathological diagnosis of renal cell carcinoma were treated with percutaneous computerized tomography guided cryoablation under conscious sedation on an outpatient basis. We retrospectively reviewed clinical data, tumor characteristics, techniques and results. Tumors with complete loss of contrast enhancement were considered successfully treated. RESULTS: A total of 21 patients with 23 tumors underwent 25 cryoablation sessions. The mean intraoperative computerized tomography scan tumor size was 2.1 cm (range 0.5 to 4.3) and the mean ice ball size was 4.1 cm (range 2.2 to 7.2). Of the patients 82.6% (19 of 23) had a single treatment. Patients were followed with postoperative scans of 4.6 to 18.3 months (mean 12.3). There were 2 recurrences. The rate of successful complete tumor ablation was influenced by various factors. Tumor location and size were the major determinants for achieving tumor eradication. CONCLUSIONS: Percutaneous renal cryoablation using computerized tomography imaging proved to be a successful technique for guiding probe placement and monitoring ice ball formation. Patient selection based on tumor size and location may aid in improved outcomes. Further study and followup are necessary to determine long-term oncological efficacy.

publication date

  • November 1, 2006

Research

keywords

  • Carcinoma, Renal Cell
  • Cryosurgery
  • Kidney Neoplasms
  • Tomography, X-Ray Computed

Identity

Scopus Document Identifier

  • 33750334670

Digital Object Identifier (DOI)

  • 10.1016/j.juro.2006.07.040

PubMed ID

  • 17070219

Additional Document Info

volume

  • 176

issue

  • 5