Therapeutic and prognostic considerations in catastrophic antiphospholipid syndrome. Review uri icon

Overview

abstract

  • Catastrophic antiphospholipid syndrome (CAPS) is a rapidly progressive life-threatening disease that causes multiple organ thromboses in the presence of antiphospholipid antibodies. High index of clinical suspicion and careful investigation are required to make an early diagnosis so that treatment with anticoagulation, corticosteroids, and plasma exchange or intravenous immunoglobulins can be initiated. Despite this multi-modal treatment, CAPS is associated with high mortality; evidence-based management recommendations do not exist due to the rarity of the condition and the lack of controlled studies. This article reviews the therapeutic and prognostic controversies that were addressed during the 1st International Symposium on CAPS.

publication date

  • July 21, 2006

Research

keywords

  • Antiphospholipid Syndrome

Identity

Scopus Document Identifier

  • 33751429820

Digital Object Identifier (DOI)

  • 10.1016/j.autrev.2006.06.013

PubMed ID

  • 17138252

Additional Document Info

volume

  • 6

issue

  • 2