Antidepressant-associated changes in semen parameters. uri icon

Overview

abstract

  • We describe 2 cases of patients referred for evaluation of male infertility who had antidepressant medication-associated changes in sperm motility and/or concentration. The physical examination and endocrinologic study findings were unremarkable in each case. Analysis of the initial semen specimens revealed oligospermia, impaired motility, and abnormal morphology in each patient while they were taking serotonin reuptake inhibitors. Repeat semen analyses performed 1 to 2 months after discontinuation of the antidepressants demonstrated marked improvements in sperm concentration and motility. Additional assessment of the potential impact of antidepressant medications on male fertility is warranted.

publication date

  • January 1, 2007

Research

keywords

  • Antidepressive Agents
  • Infertility, Male
  • Sperm Count
  • Sperm Motility

Identity

Scopus Document Identifier

  • 33846642688

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2006.10.034

PubMed ID

  • 17270655

Additional Document Info

volume

  • 69

issue

  • 1