Replication of hepatitis C virus. Review uri icon

Overview

abstract

  • Exciting progress has recently been made in understanding the replication of hepatitis C virus, a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma worldwide. The development of complete cell-culture systems should now enable the systematic dissection of the entire viral lifecycle, providing insights into the hitherto difficult-to-study early and late steps. These efforts have already translated into the identification of novel antiviral targets and the development of new therapeutic strategies, some of which are currently undergoing clinical evaluation.

publication date

  • May 8, 2007

Research

keywords

  • Hepacivirus
  • Virus Replication

Identity

Scopus Document Identifier

  • 34249024924

Digital Object Identifier (DOI)

  • 10.1038/nrmicro1645

PubMed ID

  • 17487147

Additional Document Info

volume

  • 5

issue

  • 6