Neoadjuvant systemic therapy and the surgical management of breast cancer. Review uri icon

Overview

abstract

  • Neoadjuvant chemotherapy is standard management for women who have locally advanced or inflammatory breast cancer, but can be applied to all women who may require postoperative chemotherapy for early-stage breast cancer. Disease-free survival and overall survival are equivalent between patients treated with neoadjuvant chemotherapy and patients treated with the same regimen postoperatively. Preoperative chemotherapy can offer women less morbid surgical treatment by down-staging both the primary breast tumor and axillary metastases. Finally, response to chemotherapy can inform clinicians of the chemosensitivity of the tumor, and can predict long-term outcome for women who have breast cancer.

publication date

  • April 1, 2007

Research

keywords

  • Breast Neoplasms
  • Neoadjuvant Therapy

Identity

Scopus Document Identifier

  • 34247846154

Digital Object Identifier (DOI)

  • 10.1016/j.suc.2007.02.004

PubMed ID

  • 17498534

Additional Document Info

volume

  • 87

issue

  • 2