Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report. uri icon

Overview

abstract

  • Cellular angiofibroma is a benign mesenchymal neoplasm of female and male genital tract composed of prominent vasculature and stromal spindle cells, often with admixture of adipose tissue. The tumor has histomorphologic similarities to angiomyofibroblastoma and spindle cell lipoma. Herein we describe a tumor arising in the perineal region of a 60-year-old man with morphological and immunohistochemical features of cellular angiofibroma and showing cytogenetic characteristics similar to spindle cell lipoma. To our knowledge, this is the first report of cytogenetic changes in cellular angiofibroma. The genetic overlap of these entities supports their origin from the same mesenchymal stem cell.

publication date

  • September 1, 2007

Research

keywords

  • Angiofibroma
  • Lipoma
  • Mesenchymal Stem Cells
  • Nevus, Spindle Cell

Identity

Scopus Document Identifier

  • 34548492518

Digital Object Identifier (DOI)

  • 10.1016/j.cancergencyto.2007.05.016

PubMed ID

  • 17854668

Additional Document Info

volume

  • 177

issue

  • 2