Impact of skin-subcutaneous fat layer thickness on electrical impedance myography measurements: an initial assessment. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: To determine the impact of skin-subcutaneous fat layer thickness on electrical impedance myography (EIM) measurements. METHODS: Linear 50 kHz EIM was performed on quadriceps of 62 healthy subjects (mean age 52.2+/-20.6 years) with a wide variety of skin-subcutaneous fat layer (SFL) thicknesses, as measured by ultrasound. Correlations were sought between the main EIM outcome parameter phase (theta) and SFL thickness. A multiple regression analysis was also performed for theta with SFL thickness and age as independent variables. RESULTS: Mean skin-fat thickness was significantly different (p<0.01) between men (0.76+/-0.23 cm) and women (1.43+/-0.51 cm). Neither linear nor quadratic fits produced significant correlations between theta and SFL thickness. A significant but weak positive correlation (r(2)=0.14, p<0.05) was seen between age and SFL thickness in women, but not in men. A strong negative correlation between age and theta was observed for both men (r(2)=0.48, p<0.01) and women (r(2)=0.68, p<0.01). In multiple regression analysis, age but not SFL thickness was found to have a significant association with theta. CONCLUSIONS: SFL thickness does not contribute substantially to the phase measured by linear-EIM. SIGNIFICANCE: EIM data can be interpreted confidently in individuals with varying SFL thickness.

publication date

  • September 21, 2007

Research

keywords

  • Adipose Tissue
  • Electric Impedance
  • Skinfold Thickness

Identity

PubMed Central ID

  • PMC2080664

Scopus Document Identifier

  • 35148886787

Digital Object Identifier (DOI)

  • 10.1016/j.clinph.2007.07.016

PubMed ID

  • 17889597

Additional Document Info

volume

  • 118

issue

  • 11