Analysis of monomeric mutants of HSC70: a possible relationship between oligomerization and functional properties.
Academic Article
Overview
abstract
Data of this study showed that alphaD-alphaE helices and the conserved interdomain linker are two interfaces essential not only for the self-association but also for the functional properties of rat HSC70. Self-association which is a conserved property of HSP70 seems to be important for the activity of these proteins.
