Human fear-related motor neurocircuitry. Academic Article uri icon

Overview

abstract

  • Using functional magnetic resonance imaging and an experimental paradigm of instructed fear, we observed a striking pattern of decreased activity in primary motor cortex with increased activity in dorsal basal ganglia during anticipation of aversive electrodermal stimulation in 42 healthy participants. We interpret this pattern of activity in motor neurocircuitry in response to cognitively-induced fear in relation to evolutionarily-conserved responses to threat that may be relevant to understanding normal and pathological fear in humans.

publication date

  • September 26, 2007

Research

keywords

  • Brain Mapping
  • Fear
  • Motor Cortex
  • Neural Pathways

Identity

Scopus Document Identifier

  • 36649027444

Digital Object Identifier (DOI)

  • 10.1016/j.neuroscience.2007.09.048

PubMed ID

  • 17980493

Additional Document Info

volume

  • 150

issue

  • 1