Intensity-modulated radiation therapy: supportive data for prostate cancer. Review uri icon

Overview

abstract

  • Since its introduction into clinical use in the mid-1990s, intensity-modulated radiation therapy (IMRT) has emerged as the most effective and widely used form of external-beam radiotherapy for localized prostate cancer. Multiple studies have confirmed the importance of delivering sufficiently high doses to the prostate to achieve cure. The dosimetric superiority of IMRT over conventional techniques to produce conformal dose distributions that allow for organ sparing has been shown. A growing number of reports have confirmed that IMRT is the safest way to deliver high doses of external-beam irradiation to the prostate and the regional lymph nodes. Advances in imaging and onboard verification systems continue to advance the capabilities of IMRT and have potential implications with regards to further dose escalation and hypofractionated regimens. The clinical data in support of IMRT and the associated technical aspects of IMRT treatment planning and implementation are highlighted in this review.

publication date

  • January 1, 2008

Research

keywords

  • Prostatic Neoplasms
  • Radiotherapy, Intensity-Modulated

Identity

Scopus Document Identifier

  • 36849079824

Digital Object Identifier (DOI)

  • 10.1016/j.semradonc.2007.09.007

PubMed ID

  • 18082588

Additional Document Info

volume

  • 18

issue

  • 1