Giant cell tumor of the spine. Review uri icon

Overview

abstract

  • Giant cell tumors are benign but locally aggressive neoplasms that typically affect the extremities. When involving the spine, the tumors occur predominantly in the sacrum. Gross total resection of the tumor with wide margins yields good results in terms of survival. However, it carries a significant potential for morbidity and disability. Subtotal resection with adjuvant radiation carries a risk for recurrence or, more concerning, sarcomatous malignant transformation. Endovascular tumor embolizations have also been attempted to control unresectable tumors, and have been performed with moderate degrees of success. Outcomes are analyzed outcomes following surgery, radiation therapy, and tumor embolization.

publication date

  • January 1, 2008

Research

keywords

  • Giant Cell Tumor of Bone
  • Spinal Neoplasms
  • Spine

Identity

Scopus Document Identifier

  • 37449023159

Digital Object Identifier (DOI)

  • 10.1016/j.nec.2007.09.009

PubMed ID

  • 18156047

Additional Document Info

volume

  • 19

issue

  • 1