[Radionuclide diagnosis of functional pulmonary disorders in outpatient setting].
Academic Article
Overview
abstract
AIM: To define informative value of a novel technique in radionuclide examination of microcirculatory and alveolar ventilation disorders in pulmonary diseases and to test its application possibilities in outpatient practice. MATERIAL AND METHODS: Perfusion static scintigraphy of the lungs with 99m-Tc-macrotech and ventilatory aerosol dynamic and static pulmonary scintigraphy after 99m-Tc-pentatech (DTPA analogue) inhalation were performed in 128 patients with bronchial asthma (BA), chronic obstructive bronchitis (COB) and pulmonary abscess. RESULTS: Regional perfusion and ventilation were abnormal in all the examinees with BA and COB including in lower zones of both the lungs characteristic of pulmonary emphysema. In COB ventilation-perfusion correlations were disturbed in both lungs in 87.5%, in one lung in 100% patients. In BA patients after the attack the results of ventilatory pulmonary scintigraphy should be evaluated visually (qualitatively). In pulmonary abscess regional disorders of perfusion and/or ventilation were seen in 94.6%, lack of balance V/Q in the focal zone--in 75%, in the whole affected lung--in 55.4% patients. Compensatory synchrony of ventilation-perfusion relations in impaired regional indices V/Q took place in COB patients in 37.5%, in abscess (in the affected lung)--in 42.9%. Acceleration and delay of alveolar-capillary diffusion were detected in bronchial asthma in 76.5%, COB--in 68.7%, in abscess in the affected lung--in 48.8%, in the contralateral lung--in 56.5%. CONCLUSION: Lung lesion can be assessed with ventilation-perfusion correlations and clearance of 99mTc-pentatech from the right and left lung.
