Aspirin decreases the prevalence and severity of heterotopic ossification after 1-stage bilateral total hip arthroplasty for osteoarthrosis. Academic Article uri icon

Overview

abstract

  • Heterotopic ossification (HO) is a frequent complication after total hip arthroplasty (THA). We retrospectively evaluated the prevalence and severity of HO in patients with osteoarthrosis who underwent 1-stage bilateral THA (OSBTHA) and compared those who received aspirin with those who received Coumadin for postoperative chemothromboprophylaxis. The aspirin group consisted of 66 patients (132 hips), with a mean age of 64 years (SD, 8.5). The Coumadin group consisted of 67 patients (134 hips), with a mean age of 60 years (SD, 10.2). Overall, HO was detected in 124 hips (46.6%). There were 43 hips (32.5%) with HO in the aspirin group and 81 (60.4%) in the Coumadin group (P < .00005). Aspirin significantly decreases the prevalence and severity of HO in comparison to Coumadin after OSBTHA.

publication date

  • March 28, 2008

Research

keywords

  • Anti-Inflammatory Agents, Non-Steroidal
  • Arthroplasty, Replacement, Hip
  • Aspirin
  • Ossification, Heterotopic
  • Osteoarthritis, Hip
  • Severity of Illness Index

Identity

Scopus Document Identifier

  • 58249139378

Digital Object Identifier (DOI)

  • 10.1016/j.arth.2007.11.008

PubMed ID

  • 18534420

Additional Document Info

volume

  • 24

issue

  • 2