Acute appendicitis is the most common acute surgical condition in children. Parasitic infestations are ubiquitous on a worldwide basis and are seen in the United States because of increasing international travel and emigration from developing countries. These infestations may produce symptoms of acute appendicitis, although the role of parasitic infestation in relation to appendicitis is controversial. Intestinal parasites may cause significant morbidity and mortality. We report a patient with symptoms of acute appendicitis in whom intramural parasites were found during laparoscopic surgery. Histology of the appendix specimen revealed a normal appendix. The pertinent literature is also reviewed.