Depressed mood and memory impairment before and after unilateral posteroventral pallidotomy in Parkinson's disease. Academic Article uri icon

Overview

abstract

  • This study evaluated poor mood state as a moderator of changes in verbal recall ability from before to after unilateral posteroventral pallidotomy in 54 individuals with advanced Parkinson's disease. Repeated-measures analysis of covariance (controlling for motor disease severity) indicated that left-posteroventral pallidotomy subjects with depressed mood performed more poorly on measures of verbal list learning and story recall compared to nondepressed subjects or right-posteroventral pallidotomy subjects with depressed mood both before and after surgery. The results suggest that depressed mood should be taken into account when interpreting memory test performance in Parkinson's disease surgical candidates both before and after surgery.

publication date

  • January 1, 2008

Research

keywords

  • Depressive Disorder
  • Memory Disorders
  • Pallidotomy

Identity

Scopus Document Identifier

  • 52649099031

Digital Object Identifier (DOI)

  • 10.1176/jnp.2008.20.3.357

PubMed ID

  • 18806240

Additional Document Info

volume

  • 20

issue

  • 3