Bilateral total hip arthroplasty in siblings with Stickler Syndrome. Academic Article uri icon

Overview

abstract

  • Stickler Syndrome is an infrequent autosomal dominant connective tissue disorder. The most prevalent mutation affects type II collagen gene and results in abnormalities in cartilage, vitreous and nucleus pulposus. Orthopaedic manifestations include joint hyper- mobility and pain with early development of secondary osteoarthritis. The condition has a predilection for the femoral head and patients usually present in their third to fourth decade with secondary hip arthritis. We report on two siblings with Stickler Syndrome who presented with hip osteoarthritis in their third decade of life and underwent staged bilateral total hip arthroplasties (THA). The patients experienced pain relief and improved quality of life after surgery.

publication date

  • January 1, 2007

Identity

Digital Object Identifier (DOI)

  • 10.1177/112070000701700109

PubMed ID

  • 19197843

Additional Document Info

volume

  • 17

issue

  • 1