Removal of gadolinium by dialysis: review of different strategies and techniques. Review uri icon

Overview

abstract

  • Nephrogenic systemic fibrosis (NSF) has been related to the administration of gadolinium-based contrast agents for magnetic resonance imaging studies in patients with kidney disease. After reviewing the pathophysiology of NSF, we discuss the possible factors contributing to the toxicity of gadolinium in susceptible patients, including the excessive amounts of intravenous iron and erythropoietin as well as the inflammatory states commonly seen in patients treated with hemodialysis. Since free gadolinium is the most accepted risk factor for NSF, we provide some suggestions to improve clearance of both free and chelated gadolinium using different dialysis strategies and techniques. J. Magn. Reson. Imaging 2009;30:1347-1349. (c) 2009 Wiley-Liss, Inc.

publication date

  • December 1, 2009

Research

keywords

  • Dialysis
  • Gadolinium
  • Magnetic Resonance Imaging
  • Nephrogenic Fibrosing Dermopathy
  • Renal Insufficiency

Identity

Scopus Document Identifier

  • 73649147753

Digital Object Identifier (DOI)

  • 10.1002/jmri.21981

PubMed ID

  • 19937933

Additional Document Info

volume

  • 30

issue

  • 6