The impact of multiple malignancies on patients with bladder carcinoma: a population-based study using the SEER database. Academic Article uri icon

Overview

abstract

  • PURPOSE: To date, no study has examined a population-based registry to determine the impact of multiple malignancies on survival of bladder cancer patients. Our experience suggests that bladder cancer patients with multiple malignancies may have relatively positive outcomes. MATERIALS & METHODS: We utilized data from the Surveillance Epidemiology and End Results (SEERs) database to examine survival between patients with only bladder cancer (BO) and with bladder cancer and additional cancer(s) antecedent (AB), subsequent (BS), or antecedent and subsequent to bladder cancer (ABS). RESULTS: Analyses demonstrated diminished survival among AB and ABS cohorts. However, when cohorts were substratified by stage, patients in the high-stage BS cohort appeared to have a survival advantage over high-stage BO patients. CONCLUSIONS: Bladder cancer patients with multiple malignancies have diminished survival. The survival advantage of high-stage BS patients is likely a statistical phenomenon. Such findings are important to shape future research and to improve our understanding of patients with multiple malignancies.

publication date

  • December 28, 2009

Identity

PubMed Central ID

  • PMC2801451

Scopus Document Identifier

  • 74849117182

Digital Object Identifier (DOI)

  • 10.1155/2009/406965

PubMed ID

  • 20069054

Additional Document Info

volume

  • 2009