Perimenopausal postpartum depression after conception by assisted reproductive technology.
Overview
abstract
BACKGROUND: Women conceiving after the onset of the menopausal transition may experience hormonal fluctuations that predispose them to postpartum depression. Conception by assisted reproductive technology (ART) may increase this risk. OBJECTIVE: This case report highlights the hormonal and pathophysiological changes that may contribute to the development of postpartum depression during perimenopause. METHOD: The authors report on the case of a perimenopausal woman who developed postpartum depression after conception by ART. RESULTS: The patient responded well to antidepressant treatment, estrogen replacement, and psychotherapy. CONCLUSION: Research into perimenopausal postpartum depression in the setting of ART may lead to improved screening and treatment for at-risk patients.
