Intra-arterial Thrombolytic Therapy for Acute Vertebrobasilar Artery Occlusion. Academic Article uri icon

Overview

abstract

  • We report on the results of intra-arterial thrombolysis in 11 patients with vertebrobasilar artery occlusion treated within 6 hours after onset of symptoms. Urokinase (5 patients) or recombinant tissue plasminogen activator (t-PA) (6 patients) was injected through a microcatheter conducted to the thrombus. Eight patients showed recanalization of the thrombus. The outcome was excellent in 5 patients, good in 2 patients, and poor in one patient. Recanalization could not be achieved in 3 of the 11 procedures; all patients in whom recanalization failed died. There were no hemorrhagic complications after thrombolysis. Two patients with residual stenosis after thrombolysis underwent successful percutaneous transluminal angioplasty (PTA) to prevent reocclusion. Intra-arterial thrombolysis for vertebrobasilar artery occlusion is a safe and effective treatment if it is performed within 6 hours.

publication date

  • May 15, 2001

Identity

Scopus Document Identifier

  • 12644262394

Digital Object Identifier (DOI)

  • 10.1177/15910199970030S211

PubMed ID

  • 20678387

Additional Document Info

volume

  • 3 Suppl 2