Targeted cancer therapies. Editorial Article uri icon

Overview

abstract

  • With unprecedented understanding of molecular events underlying human cancer in this genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers to which tumors are potentially addicted to have been developed and continue to be developed. These targeted cancer therapies are being actively tested in clinical trials with mixed successes. This editorial provides an overview on successful targeted cancer drugs on the market and those drugs that are in late clinical development stages. Importantly, the article lays out main challenges in developing molecular targeted therapies and potential path forward to overcome these challenges, as well as opportunities for China in this new era of targeted agents. The editorial serves as an introduction to the Targeted Cancer Therapies series that will review in depth of major pathways and drugs targeting these pathways to be published in the coming issues of the Chinese Journal of Cancer.

publication date

  • January 1, 2011

Research

keywords

  • Antineoplastic Agents
  • Molecular Targeted Therapy
  • Neoplasms

Identity

PubMed Central ID

  • PMC4012258

Scopus Document Identifier

  • 79954603808

Digital Object Identifier (DOI)

  • 10.5732/cjc.010.10553

PubMed ID

  • 21192839

Additional Document Info

volume

  • 30

issue

  • 1