Risk factors for white matter changes detected by magnetic resonance imaging in the elderly. Academic Article uri icon

Overview

abstract

  • We found increased age (p = 0.001) and history or evidence of stroke (p = 0.016) to be significant independent multivariate predictors of the presence and severity of leukoencephalopathy on magnetic resonance imaging brain scans in a mixed population of 35 elderly psychiatric patients and 25 neurologically healthy elderly volunteers. These results suggest that subcortical ischemia, as well as age-related changes that may not be vascular in origin, contribute to the emergence of periventricular and other deep white matter hyperintensities that are commonly seen on the magnetic resonance imaging brain scans of older adults.

publication date

  • October 1, 1990

Research

keywords

  • Brain
  • Leukoencephalopathy, Progressive Multifocal

Identity

Scopus Document Identifier

  • 0025027983

Digital Object Identifier (DOI)

  • 10.1161/01.str.21.10.1424

PubMed ID

  • 2219207

Additional Document Info

volume

  • 21

issue

  • 10