Enlightening the impact of immunogenic cell death in photodynamic cancer therapy.
Overview
abstract
EMBO J 31 5, 1062–1079 (2012); published online January 17 2012 In this issue of The EMBO Journal, Garg et al (2012) delineate a signalling pathway that leads to calreticulin (CRT) exposure and ATP release by cancer cells that succumb to photodynamic therapy (PTD), thereby providing fresh insights into the molecular regulation of immunogenic cell death (ICD).