A novel device to apply controlled flexion and extension to the rat knee following anterior cruciate ligament reconstruction. Academic Article uri icon

Overview

abstract

  • We designed and validated a novel device for applying flexion-extension cycles to a rat knee in an in vivo model of anterior cruciate ligament reconstruction (ACL-R). Our device is intended to simulate rehabilitation motion and exercise post ACL-R to optimize physical rehabilitation treatments for the improved healing of tendon graft ligament reconstructions. The device was validated for repeatability of the knee kinematic motion by measuring the force versus angular rotation response from repeated trials using cadaver rats. The average maximum force required for rotating an ACL reconstructed rat knee through 100 degrees of flexion-extension was 0.4 N with 95% variability for all trials within ±0.1 N.

publication date

  • April 1, 2012

Research

keywords

  • Anterior Cruciate Ligament Reconstruction
  • Hindlimb

Identity

PubMed Central ID

  • PMC3650617

Scopus Document Identifier

  • 84860440727

Digital Object Identifier (DOI)

  • 10.1177/036354658801600307

PubMed ID

  • 22667683

Additional Document Info

volume

  • 134

issue

  • 4