Adjuvant therapy in stage I carcinoma of the breast: the influence of multigene analyses and molecular phenotyping. Conference Paper uri icon

Overview

abstract

  • A consensus conference was held in order to provide guidelines for the use of adjuvant therapy in patients with Stage I carcinoma of the breast, using traditional information, such as tumor size, microscopic character, Nottingham index, patient age and co-morbidities, but also incorporating steroid hormone and Her-2-neu data as well as other immunohistochemical markers. The role of the genetic analysis of breast cancer and proprietary gene prognostic signatures was discussed, along with the molecular profiling of breast cancers into several groups that may predict prognosis. These molecular data are not currently sufficiently mature to make them part of decision making algorithms of recommendations for the treatment of individual patients.

publication date

  • January 1, 2012

Research

keywords

  • Breast Neoplasms
  • Transcriptome

Identity

Scopus Document Identifier

  • 84863646635

Digital Object Identifier (DOI)

  • 10.1111/j.1524-4741.2012.01264.x

PubMed ID

  • 22759093

Additional Document Info

volume

  • 18

issue

  • 4