Experience with the combination of dutasteride and tamsulosin in the long-term management of benign prostatic hyperplasia. Academic Article uri icon

Overview

abstract

  • Lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) commonly affect older men. These bothersome symptoms can lead to a decreased quality of life. Currently, two classes of drugs - α-adrenergic blockers and 5α-reductase inhibitors - are prescribed to treat LUTS secondary to BPH. Due to their different mechanisms of action, these medications work in a synergistic manner. Trials of combination therapy have been conducted to assess its effect compared with monotherapy. Current data support combination therapy in men with moderately enlarged prostates and moderate to severe symptoms.

publication date

  • October 1, 2012

Identity

PubMed Central ID

  • PMC3441136

Scopus Document Identifier

  • 84871912150

Digital Object Identifier (DOI)

  • 10.1177/1756287212457115

PubMed ID

  • 23024707

Additional Document Info

volume

  • 4

issue

  • 5