Optimal detection pinhole for lowering speckle noise while maintaining adequate optical sectioning in confocal reflectance microscopes. Academic Article uri icon

Overview

abstract

  • Coherent speckle influences the resulting image when narrow spectral line-width and single spatial mode illumination are used, though these are the same light-source properties that provide the best radiance-to-cost ratio. However, a suitable size of the detection pinhole can be chosen to maintain adequate optical sectioning while making the probability density of the speckle noise more normal and reducing its effect. The result is a qualitatively better image with improved contrast, which is easier to read. With theoretical statistics and experimental results, we show that the detection pinhole size is a fundamental parameter for designing imaging systems for use in turbid media.

publication date

  • August 1, 2012

Research

keywords

  • Algorithms
  • Artifacts
  • Image Enhancement
  • Image Interpretation, Computer-Assisted
  • Microscopy, Confocal
  • Nephelometry and Turbidimetry
  • Skin

Identity

PubMed Central ID

  • PMC3412991

Scopus Document Identifier

  • 84874982581

Digital Object Identifier (DOI)

  • 10.1117/12.908374

PubMed ID

  • 23224184

Additional Document Info

volume

  • 17

issue

  • 8