Prognostic value of the immune microenvironment in lung adenocarcinoma. Academic Article uri icon

Overview

abstract

  • We analyzed the immune microenvironment in the neoplastic and stromal components of Stage I lung adenocarcinoma lesions, finding that a high ratio of tumor-infiltrating FOXP3+ regulatory T cells to CD3+ lymphocytes, an elevated expression of the interleukin-7 receptor, as well as a reduced expression of the interleukin-12 receptor β2 all constitute independent factors of poor prognosis.

publication date

  • May 1, 2013

Identity

PubMed Central ID

  • PMC3667898

Scopus Document Identifier

  • 61349123540

Digital Object Identifier (DOI)

  • 10.1016/j.ejca.2008.12.006

PubMed ID

  • 23762792

Additional Document Info

volume

  • 2

issue

  • 5