Inside-out connections: the ER meets the plasma membrane. uri icon

Overview

abstract

  • Junctions that connect the endoplasmic reticulum (ER) and the plasma membrane (PM) are unique yet ubiquitous subcellular compartments. Giordano et al. now report that extended synaptotagmins (E-Syts) promote their formation, providing fundamental insight into the molecular machinery controlling ER and plasma membrane crosstalk.

publication date

  • June 20, 2013

Research

keywords

  • Calcium
  • Cell Membrane
  • Endoplasmic Reticulum
  • Phosphatidylinositol 4,5-Diphosphate
  • Synaptotagmins

Identity

PubMed Central ID

  • PMC6783275

Scopus Document Identifier

  • 84879338463

Digital Object Identifier (DOI)

  • 10.1016/j.cell.2013.05.054

PubMed ID

  • 23791170

Additional Document Info

volume

  • 153

issue

  • 7