Characterisation of polymer shelled microbubbles in wall less flow phantom using high frequency ultrasound and video microscopy. Academic Article uri icon

Overview

abstract

  • A high frequency ultrasound pulse echo system and a video microscope were combined to investigate the relationship between backscatter from polymer shelled ultrasound contrast agents (UCAs) and their diameter. Individual UCAs (manufactured by Point Biomedical or Philips Research) were imaged while being sonicated with 40 MHz tone bursts. The backscatter magnitude produced by the Philips UCAs was proportional to UCA size, which is consistent with theoretically predicted behaviour of encapsulated microbubbles driven at frequencies above resonance. Despite being smaller, the Point UCAs produced a backscatter magnitude twice that of Philips UCAs, indicating that Point UCAs might behave quasi-resonantly when excited at 40 MHz.

publication date

  • November 1, 2011

Identity

PubMed Central ID

  • PMC3686316

Scopus Document Identifier

  • 83055166920

Digital Object Identifier (DOI)

  • 10.1179/1758897911Y.0000000005

PubMed ID

  • 23795208

Additional Document Info

volume

  • 3

issue

  • 2