Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys. Academic Article uri icon

Overview

abstract

  • Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not persist longitudinally.

publication date

  • August 7, 2013

Research

keywords

  • Genetic Variation
  • Milk, Human
  • Simian Acquired Immunodeficiency Syndrome
  • Simian Immunodeficiency Virus

Identity

PubMed Central ID

  • PMC3807282

Scopus Document Identifier

  • 84886887750

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0009294

PubMed ID

  • 23926337

Additional Document Info

volume

  • 87

issue

  • 20