Calculating the Bending Modulus for Multicomponent Lipid Membranes in Different Thermodynamic Phases. Academic Article uri icon

Overview

abstract

  • We establish a computational approach to extract the bending modulus, KC , for lipid membranes from relatively small-scale molecular simulations. Fluctuations in the splay of individual pairs of lipids faithfully inform on KC in multicomponent membranes over a large range of rigidities in different thermodynamic phases. Predictions are validated by experiments even where the standard spectral analysis-based methods fail. The local nature of this method potentially allows its extension to calculations of KC in protein-laden membranes.

publication date

  • September 10, 2013

Identity

PubMed Central ID

  • PMC3770052

Scopus Document Identifier

  • 84884186161

Digital Object Identifier (DOI)

  • 10.1021/ct400492e

PubMed ID

  • 24039553

Additional Document Info

volume

  • 9

issue

  • 9