Routine histopathologic characteristics can predict oncotype DX(TM) recurrence score in subsets of breast cancer patients. Academic Article uri icon

Overview

abstract

  • This study assessed whether routine pathologic parameters could predict Oncotype DX(TM) recurrence score (RS) in 72 breast cancers diagnosed from 2008-2012. Comparing patients with low RS (0-17) vs. intermediate RS (18-30) vs. high RS (>30), the mean Nottingham score increased (5.5 vs. 6.3 vs. 7.2, respectively, p = .001) and the mean PR Allred score decreased (6.7 vs. 4.9 vs. 3.3, respectively, p = .001). A high RS was least likely for low-grade tumors (0% had high RS, p = .005), and strong PR positivity (9% had high RS, p = .017). A low RS was least likely for cancers that were both high grade and PR weak/negative.

publication date

  • November 1, 2013

Research

keywords

  • Breast Neoplasms
  • Decision Support Techniques
  • Genetic Testing

Identity

Scopus Document Identifier

  • 84887228047

Digital Object Identifier (DOI)

  • 10.3109/07357907.2013.849725

PubMed ID

  • 24164299

Additional Document Info

volume

  • 31

issue

  • 9