Fertility in patients with congenital adrenal hyperplasia. Review uri icon

Overview

abstract

  • Congenital adrenal hyperplasia (CAH) is the most frequently encountered genetic steroid disorder affecting fertility. Steroid hormones play a crucial role in sexual development and reproductive function; patients with either 21- hydroxylase or 11β-hydroxylase deficiency thus face immense challenges to their fertility. Given the relevance of CAH in reproductive medicine as well as the diagnostic challenges posed by the phenotypic overlap with polycystic ovary syndrome, we review the reproductive pahophysiology of both classic and nonclassic CAH and present contemporary treatment options.

publication date

  • December 17, 2013

Research

keywords

  • Adrenal Hyperplasia, Congenital
  • Fertility

Identity

Scopus Document Identifier

  • 84893453976

Digital Object Identifier (DOI)

  • 10.1016/j.fertnstert.2013.11.002

PubMed ID

  • 24355046

Additional Document Info

volume

  • 101

issue

  • 2