Non-Hodgkin's lymphomas, version 2.2014. uri icon

Overview

abstract

  • Non-Hodgkin's lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B lymphocytes, T lymphocytes, or natural killer cells. Follicular lymphoma (FL) is the most common subtype of indolent NHL, accounting for approximately 22% of all newly diagnosed cases of NHL. The incorporation of rituximab to chemotherapy regimens has become a widely accepted standard of care for first-line therapy for patients with FL. Maintenance and consolidation therapy with rituximab and radioimmunotherapy have also been associated with improved progression-free survival in patients experiencing response to first-line therapy. Despite therapeutic advances that have improved outcomes, FL is generally considered a chronic disease characterized by multiple recurrences with current therapies. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with FL.

authors

  • Zelenetz, Andrew
  • Gordon, Leo I
  • Wierda, William G
  • Abramson, Jeremy S
  • Advani, Ranjana H
  • Andreadis, C Babis
  • Bartlett, Nancy
  • Bellam, Naresh
  • Byrd, John C
  • Czuczman, Myron S
  • Fayad, Luis E
  • Fisher, Richard I
  • Glenn, Martha J
  • Harris, Nancy Lee
  • Hoppe, Richard T
  • Horwitz, Steven Michael
  • Kelsey, Christopher R
  • Kim, Youn H
  • Krivacic, Susan
  • LaCasce, Ann S
  • Nademanee, Auayporn
  • Porcu, Pierluigi
  • Press, Oliver
  • Rabinovitch, Rachel
  • Reddy, Nishitha
  • Reid, Erin
  • Sokol, Lubomir
  • Swinnen, Lode J
  • Tsien, Christina
  • Vose, Julie M
  • Yahalom, Joachim
  • Zafar, Nadeem
  • Dwyer, Mary
  • Sundar, Hema

publication date

  • June 1, 2014

Research

keywords

  • Antibodies, Monoclonal, Murine-Derived
  • Lymphoma, Follicular
  • Lymphoma, Non-Hodgkin
  • Neoplasm Recurrence, Local

Identity

Scopus Document Identifier

  • 84902504593

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2014.0086

PubMed ID

  • 24925202

Additional Document Info

volume

  • 12

issue

  • 6