Web based pathology assessment in RTOG 98-04. Academic Article uri icon

Overview

abstract

  • AIMS: Radiation Therapy Oncology Group 98-04 sought to identify women with ‘good risk’ ductal carcinoma in situ (DCIS) who receive no significant benefit from radiation. Enrolment criteria excluded close or positive margins and grade 3 disease. To ensure reproducibility in identifying good risk pathology, an optional web based teaching tool was developed and a random sampling of 10% of submitted slides were reviewed by a central pathologist. METHODS: Submitting pathologists were asked to use the web based teaching tool and submit an assessment of the tool along with the pathology specimen form and DCIS H&E stained slide. Per protocol pathology was centrally reviewed for 10% of the cases. RESULTS: Of the 55 DCIS cases reviewed, three had close or positive margins and three were assessed to include grade 3 DCIS, therefore 95% of DCIS cases reviewed were correctly graded, and 89% reviewed were pathologically appropriate for enrolment. Regarding the teaching tool, 13% of DCIS cases included forms that indicated the website was used. One of these seven who used the website submitted DCIS of grade 3. CONCLUSIONS: Central review demonstrates high pathological concordance with enrolment eligibility, particularly with regard to accurate grading. The teaching tool appeared to be underused.

publication date

  • September 1, 2014

Research

keywords

  • Breast Neoplasms
  • Carcinoma, Intraductal, Noninfiltrating
  • Computer-Assisted Instruction
  • Education, Medical, Continuing
  • Internet
  • Pathology, Clinical

Identity

PubMed Central ID

  • PMC4145412

Scopus Document Identifier

  • 84906939841

Digital Object Identifier (DOI)

  • 10.1136/jclinpath-2014-202370

PubMed ID

  • 24989024

Additional Document Info

volume

  • 67

issue

  • 9