Adolescent prediabetes in a high-risk Middle East country: a cross-sectional study. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: To estimate the prevalence of prediabetes in adolescents living in a high-risk country and to detect risk factors associated with this disorder. DESIGN: Survey questionnaire combined with physical measurements and blood sugar determination. SETTING: Doha, capital city of Qatar. PARTICIPANTS: A total of 1694 male and female students aged 11-18 years without previously diagnosed diabetes enrolled in four schools. MAIN OUTCOME MEASURE: Blood sugar measurements. Other measured variables included gender, height, weight, abdominal circumference, country of origin, family history of diabetes and frequency of exercise. RESULTS: Using a random blood sugar ≥7.8 mmol/L or a fasting blood sugar ≥5.5 mmol/L as cutpoints, we identified 4.2% of students (56 boys, 15 girls) as probable prediabetics. In a multivariate model, being boys (OR 3.2, 95% CI 1.7-6.2), having a diabetic parent (OR 1.9, 95% CI 1.1-3.2) or having a waist-to-height ratio >0.5 (OR 1.8, 95% CI 1.1-3.0) were significantly associated with being a prediabetic. The parental origin of diabetes had a differential effect upon blood sugar. The mean random blood sugar in students with a maternal inheritance pattern of diabetes was 5.61 mmol/L ± 1.0, compared to 5.39 mmol/L ± 0.89 in students with a paternal inheritance pattern (p = 0.02). CONCLUSIONS: In a country with a high risk of adult diabetes, we identified 4.2% of students aged 11-18 as being prediabetic. Risk factors associated with prediabetes included male gender, family history of diabetes and waist-to-height ratio >0.5.

publication date

  • July 8, 2014

Identity

PubMed Central ID

  • PMC4100242

Scopus Document Identifier

  • 84947027994

Digital Object Identifier (DOI)

  • 10.1177/2054270414536550

PubMed ID

  • 25289147

Additional Document Info

volume

  • 5

issue

  • 8