CDK6 is a regulator of stem cells "Egr" to wake up.
Overview
abstract
In this issue of Blood, Scheicher et al show that cyclin-dependent kinase 6 (CDK6) has a novel role in the regulation of both normal and leukemic stem cells. It acts as a transcriptional suppressor of Egr1, enabling it to control both normal and leukemic stem cell activation.
