Quantitative precision of optical frequency domain imaging: direct comparison with frequency domain optical coherence tomography and intravascular ultrasound. Academic Article uri icon

Overview

abstract

  • No systematic validation study is available with optical frequency domain imaging (OFDI), directly compared with frequency domain optical coherence tomography (FD-OCT) and intravascular ultrasound (IVUS). Controversy also remains about the impact of different stent contour tracing methods by OFDI/FD-OCT. In vitro: coronary phantom models (1.51-5.04 mm) were imaged with OFDI, FD-OCT, and IVUS, demonstrating excellent quantitative precision with a slight overestimation of mean lumen diameter (difference 0.01-0.02 mm). In vivo: corresponding 64 OFDI/IVUS images of stented coronary segments from 20 swines were analyzed. Minimum lumen area by OFDI was larger than IVUS at baseline (P < 0.001), whereas it was smaller than IVUS at follow-up. When stent was traced at leading edges of struts by OFDI, minimum stent area was similar between OFDI and IVUS (P = 0.60). When traced at the highest intensity points of struts by OFDI, it was significantly larger in OFDI than in IVUS (P < 0.001). Three modalities have clinically acceptable precision across the wide range of lumen diameters. In vivo measurements by OFDI and IVUS could slightly be discrepant depending on the parameters and time points. In stent assessment by OFDI, the 2 methods led to a small but systematic difference; therefore, consistency in methodology is advised for comparative studies.

authors

  • Kobayashi, Yuhei
  • Kitahara, Hideki
  • Tanaka, Shigemitsu
  • Okada, Kozo
  • Kimura, Takumi
  • Ikeno, Fumiaki
  • Yock, Paul G
  • Fitzgerald, Peter J
  • Honda, Yasuhiro

publication date

  • August 14, 2015

Research

keywords

  • Coronary Vessels
  • Tomography, Optical Coherence
  • Ultrasonography, Interventional

Identity

PubMed Central ID

  • PMC4826428

Scopus Document Identifier

  • 84964077733

Digital Object Identifier (DOI)

  • 10.1136/heart.89.2.133

PubMed ID

  • 26271203

Additional Document Info

volume

  • 31

issue

  • 2