Myoepithelial carcinoma of the extremity: Response to isolated limb infusion. uri icon

Overview

abstract

  • We report our experience with two patients with myoepithelial carcinoma (MEC) of the extremity. An 83-year-old male and a 35-year-old female were treated with standard isolated limb infusion (ILI), using melphalan and dactinomycin. The first patient had a complete response (CR) that was sustained for two and a half years, until he developed a regional lymph node metastasis. The second patient had a 4.7 cm tumor located on her left hand with metastasis to the ipsilateral axillary lymph nodes. Initial treatment consisted of ILI and left axillary lymphadenectomy. The primary tumor regressed and showed signs of central necrosis, measuring 2.8 cm after 1 month. Though she was continuing to respond, a decision was made by her orthopedic surgeon to administer neoadjuvant radiation followed by surgical resection.

publication date

  • August 19, 2015

Research

keywords

  • Antineoplastic Combined Chemotherapy Protocols
  • Chemotherapy, Cancer, Regional Perfusion
  • Extremities
  • Myoepithelioma

Identity

Scopus Document Identifier

  • 84945474370

Digital Object Identifier (DOI)

  • 10.1002/jso.24014

PubMed ID

  • 26288004

Additional Document Info

volume

  • 112

issue

  • 5